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Insulin Resistance

Insulin resistance has been defined as the inability of muscle, fat and liver cells to utilize insulin properly. Studies have noted that a resistance to insulin increases the chance of diabetes as well as heart disease and other ailments. See below for related articles on insulin resistance.

Taking A Closer Look At Insulin Resistance Syndrome
With this in mind, it? In their study, Basu et. There is plenty of literature supporting the link between obesity and insulin resistance.

Featured Content from Podiatry Today



Management of Insulin Resistance in the Elderly Patient With Diabetes
Management of Insulin Resistance in the Elderly Patient With Diabetes Management of Insulin Resistance in the Elderly Patient With Diabetes Ilan Gabriely, MD, and Nir Barzilai, MD From the Department of Medicine, Divisions of Geriatrics, Endocrinology, and the Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, NY. Physical training also increases insulin sensitivity (ie, patients respond better to insulin injection or endogenous insulin). The effect of ...

Featured Content from Clinical Geriatrics



An Algorithim for Managing Type 2 Diabetes: A Focus on the Disease Process, Not Just the Sugar
This supplement reviews the pathophysiology of type 2 diabetes, the oral pharmacologic treatment of type 2 diabetes, and proposed treatment algorithms, which are stratified based on fasting plasma glucose levels. Two recently stopped studies, the Diabetes Prevention Trial Type 1 (DPT-1) and the European Nicotinamide Diabetes Intervention Trial (ENDIT), showed no benefit of insulin (oral or low-dose injected) or nicotinamide, respectively.26,27 Trials that have been traditionally thought of ...

Featured Content from Annals of Long-Term Care




August 2004
An Algorithm for Managing Type 2 Diabetes: A Focus on the Disease Process, Not Just the Sugar

This supplement reviews the pathophysiology of type 2 diabetes, the oral pharmacologic treatment of type 2 diabetes, and proposed treatment algorithms, which are stratified based on fasting plasma glucose levels. Two recently stopped studies, the Diabetes Prevention Trial Type 1 (DPT-1) and the European Nicotinamide Diabetes Intervention Trial (ENDIT), showed no benefit of insulin (oral or low-dose injected) or nicotinamide, respectively.26,27 Trials that have been traditionally thought of ...

Featured Content from Annals of Long-Term Care



CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes
CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes By James B. Meigs, M.D., M.P.H. 7 During nine years of follow-up of over 5,000 newly diagnosed patients with type 2 diabetes in the United Kingdom Prospective Diabetes Study (UKPDS), CVD complications outnumbered microvascular complications an overwhelming 70 to 1.8 Given the increasing prevalence of ...

Featured Content from Clinical Geriatrics



Improving Disease Management with New Treatments for Type 2 Diabetes Mellitus
Insulin resistance leads to a compensatory increase in the circulating insulin level, which overcomes the relative block in insulin action and prevents an increase in glucose levels (Figure 1). Eventually, a defect affecting the secretion of insulin by the beta cell impairs its ability to sustain the heightened level of insulin output required to balance the tissue insulin resistance. When used in combination with drugs that increase insulin levels, including sulfonylureas, repaglinide, or ...

Featured Content from Clinical Geriatrics



Diabetes Mellitus: Present and Future Preventive Strategies?Part II
Part II Aspects of Diabetes Mellitus: Diabetes Mellitus: Present and Future Preventive Strategies? lifestyle modification in preventing the primary outcome of progression to diabetes based on 1997 American Diabetes Association (ADA) criteria. Only a minority of all persons with type 2 diabetes are believed to have a single-gene defect, such as maturity-onset diabetes of the young (mutated MODY gene), syndrome of insulin resistance (insulin receptor defect), and maternally inherited diabetes ...

Featured Content from Clinical Geriatrics



Cutaneous Manifestations of Diabetes
Abstract: Diabetes mellitus is a chronic disease of metabolic dysregulation involving the abnormal metabolism of glucose. Diabetes has a significant impact on the healthcare costs of the Western world. Nearly all patients with diabetes eventually develop cutaneous manifestations of the disease. Cutaneous signs of the disease can heighten the suspicions of a physician regarding the diagnosis of diabetes. This article will focus on the clinical features, pathogenesis, and treatment modalities of the various dermatologic manifestations of the disease ranging from the more benign granuloma annulare to the more sinister diabetic ulcer.

Featured Content from Wounds Research



Cardiovascular and Health News
Cardiovascular and Health News Cardiovascular and Health News Focus on Cardiovascular Risk and the Patient with Diabetes For persons with type 2 diabetes, cardiovascular disease complications, including coronary artery disease, stroke, and peripheral vascular disease, exact the greatest toll on their health. Source: www.diabetes.org Nontraditional Risk Factors Peculiar to Diabetes Linked with Coronary Artery Disease Several nontraditional risk factors exclusive to diabetes have been ...

Featured Content from Clinical Geriatrics



Atherosclerotic Vascular Disease and Diabetes in the Older Adult; Part I: Understanding Pathogenic Mechanisms and Identifying Risk Factors
Atherosclerotic Vascular Disease and Diabetes in the Older Adult; Part I: Understanding Pathogenic Mechanisms and Identifying Risk Factors Aspects of Diabetes Mellitus: Atherosclerotic Vascular Disease and Diabetes in the Older Adult; Part I: Understanding Pathogenic Mechanisms and Identifying Risk Factors- Jennifer Wheaton, DO, and Sally M. Pinkstaff, MD, PhD Click here to download full article in PDF format RS is a 75-year-old Caucasian man with essential hypertension and type 2 diabetes ...

Featured Content from Clinical Geriatrics



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