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Diabetic Skin
One-third of the 20.8 million patients with diabetes develop cutaneous manifestations of the disease. Onychomycosis is reportedly 2.8 times more likely among patients with diabetes than those without diabetes. With maladies ranging from xerosis and onychomycosis to diabetic bullae and Candida infections, it is increasingly important to keep aware of pertinent information relating to the field. Below are several key articles that highlight diabetic skin conditions.
Is A Unique Topical Ideal For Diabetic Skin Care?
For practitioners, the simplest of preventative measures may be the key to combating diabetic skin conditions. ? Both Drs.
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Disorders of the Diabetic Skin
Necrobiosis Lipoidica Diabeticorum Necrobiosis lipoidica diabeticorum (NLD) is not exclusive to diabetes. Symptoms include velvety, hyperpigmented plaques. There are several ways to treat this disorder.
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Treatment of Chronic Leg Ulcers with a Human Fibroblast-Derived Dermal Substitute: A Case Series of 114 Patients
Abstract: Leg ulceration typically is a chronic recurring condition with costs both to patients and to society. The first line of treatment is to correct the underlying etiology of the ulcer. This is not always possible, and for these hard-to-heal ulcers there are new treatment options, such as growth factors and biological skin substitutes. The objective of this study was to assess the effectiveness of a tissue-engineered human fibroblast-derived dermal substitute (HDS) (Dermagraft®, Smith & Nephew Inc., Largo, Florida) in the treatment of leg ulcers of varying etiologies. The data presented in this case series represent the results from the treatment of 114 patients with 151 chronic leg ulcers treated with HDS. This study showed that HDS was effective, well tolerated, and can be used in the treatment of hard-to-heal chronic ulcers of various origins. The overall reduction in size of all the ulcers was 63 percent. Especially good results were obtained in patients with rheumatic ulcers. In conclusion, it can be stated that HDS has a role in the treatment of leg ulcers of various origins as part of a comprehensive treatment package. More studies about cost effectiviness and optimal patient selection are needed.
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Current Concepts In Managing The Wound Microenvironment
When it comes to healing chronic ulcerations, one must have a strong understanding of the cellular dysfunction that occurs with these ulcers. Accordingly, these authors offer a closer look at the dynamic nature of wound healing and how to strive for the right balance of growth factors, cytokines and proteases in the wound bed.
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June 2007
Visit http://www.smith-nephew.com or http://www.blueskymedical.com for more information.Swiss-American Skin and Wound Care Program Offers Promising Outcomes Swiss-American Products, Inc. (Dallas, Tex) has analyzed historical data from the Centers for Medicare and Medicaid Services (CMS) to evaluate long-term care quality measures. Visit http://...
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Ortec Partners with PDI for Launch of OrCel into Burn Market
Ortec Partners with PDI for Launch of OrCel into Burn Market Industry News: Ortec Partners with PDI for Launch of OrCel into Burn Market - Ortec International, Inc., a tissue-engineering company, announced that it will use a dedicated sales force provided by PDI, a pharmaceutical and medical device and diagnostics sales and marketing company, to target the donor site burn market. Ortec International, Inc., is...
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August 2006
August 2006 Product News: August 2006 - Coloplast Introduces SeaSorb®-Ag Alginate Dressing Coloplast Corp. (Marietta, Ga) introduces SeaSorb®-Ag Alginate Dressing with Silver. The dressing provides clinicians superior absorption performance and exudate management. Visit http://www.AcryMed.com for more information.
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The Choice of Diabetic Foot Ulcer Classification in Relation to the Final Outcome
Abstract: The objective of this paper is to present a new classification for diabetic foot ulcers, the two-dimensional Van Acker/Peter classification (VA/P), and test its prognostic value in comparison with the one-dimensional Megit/Wagner classification. Research Design and Methods: A group of patients visiting the UZA Diabetic Foot Clinic between January, 1992, and December, 1997, was analyzed retrospectively. Clinical descriptions and photographic images of their ulcers were collected of all patients. All ulcers were coded by one investigator. Only files with data on healing outcome were included. The VA/P Classification has a horizontal axis with clinical assessment of depth and grade of infection and a physiopathological vertical axis. Both classifications were evaluated according to healing with or without amputation and to duration of healing. Results: Study population consisted of 121 patients with a total of 253 ulcers. Of these, 88 percent healed without amputation. About 60 percent of the ulcers were located on the toes, accounting for 83.3 percent of all amputations. Twenty-one out of thirty (70%) amputations occurred in the vascular group DE (VA/P). Both ulcer classifications (Wagner and VA/P) showed good mutual correlation, but no correlation existed between the two parts of the VA/P classification. Therefore, both classifications deliver additional information and can be used in a complementary way. Furthermore, only in the Wagner classification a significant association was found with duration of healing of the ulcer. Conclusions: The Wagner classification remains a perfectly usable instrument on the clinical and prognostic levels. In a multicenter research situation, a more detailed description, such as the VA/P classification, is needed, particularly in case of Wagner 3 ulcers.
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Emerging Treatments in Diabetic Wound Care
Abstract: This paper reviews the physiology of wound healing and properties of the ?ideal? dressing and also reviews advanced wound therapeutics and dressings, such as growth factors and biological skin substitutes.
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What Emerging Research Reveals About Hyperglycemia And Vascular Imbalances
Diabetic neuropathy has been identified as an important risk factor for foot problems in the diabetic patient. However, little is known about the epidemiology and natural history of diabetic neuropathy. That is not to say that other etiologies may play a role.
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