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Cardiovascular Disease
Up to 60 percent of adults with diabetes have high blood pressure and most of those people have one or more lipid abnormalities, such as increased triglycerides, low HDL cholesterol or elevated LDL cholesterol, placing them at a high risk for cardiovascular disease. See below for related articles.
Psychopharmacology in the Elderly Person with Cardiovascular Disease
Mental illness and cardiovascular disease are seen both individually and concomitantly with significant frequency in the elderly, with two of the most prevalent mental disorders being depression and psychosis. Proper pharmacologic treatment of both conditions using antidepressant and antipsychotic agents includes an understanding of various pharmacokinetic and pharmacodynamic considerations (eg, drug absorption, distribution, metabolism, excretion), as well as the direct effect these agents may have on elderly persons, who are often more sensitive to the therapeutic effects as well as the adverse effects of these drugs. Cardiotoxic effects (such as QT interval prolongation), increased cerebrovascular events, metabolic dysfunction, and increased risk of death have been attributed to some of these medications. The coadministration of psychoactive and cardiovascular-related medications is also common in this population, and adds particular complexity to the task of choosing an appropriate drug regimen that provides maximum clinical efficacy with minimal drug-drug interaction. Both older and newer generations of agents will be discussed here. (Annals of Long-Term Care: Clinical Care and Aging 2006;14[5]:34-45)
Featured Content from Annals of Long-Term Care
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Predictors of Cardiovascular Death: The Normative Aging Study--1963-1998
In these four regression models we included (a) systolic blood pressure alone, (b) diastolic blood pressure alone, (c) both systolic blood pressure and diastolic blood pressure, and (d) pulse pressure as a representation of blood-pressure status, respectively. Percentile distributions of systolic blood pressure, diastolic blood pressure, and pulse pressure by age groups are presented in Table II. When systolic and diastolic blood pressure were both included in model 3, the regression ...
Featured Content from Clinical Geriatrics
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Cardiovascular and Health News
Cardiovascular and Health News Cardiovascular and Health News Focus on Cardiovascular Risk and the Patient with Diabetes For persons with type 2 diabetes, cardiovascular disease complications, including coronary artery disease, stroke, and peripheral vascular disease, exact the greatest toll on their health. Source: www.diabetes.org Nontraditional Risk Factors Peculiar to Diabetes Linked with Coronary Artery Disease Several nontraditional risk factors exclusive to diabetes have been ...
Featured Content from Clinical Geriatrics
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Aging and Menopause: Targeting Strategies for Therapies
Advancing age is also accompanied by an increased vulnerability to chronic diseases including cancer, bone and muscle atrophy, cardiovascular disease, mental disorders, diabetes mellitus, and immune dysfunction.1-3 Because humans age at different rates, biological and chronological age represent distinct measures, and the mechanisms that mediate the biological aging process in humans remain an enigma. Although women have little control over slowing down the onset of menopause, hormone ...
Featured Content from Clinical Geriatrics
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Diabetes Mellitus and Cardiovascular Disease in the Older Woman
The HERS study is the first large trial on estrogen plus progestin replacement therapy in postmenopausal women and its effect on cardiovascular risk. Trials of ERT are especially needed in diabetic women, given their very high risks for CHD and stroke.16 Hypertension in Diabetic Women Diabetes mellitus and hypertension are interrelated diseases. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: The Postmenopausal Estrogen/Progestin ...
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Erectile Dysfunction and Cardiovascular Disease
Erectile Dysfunction and Cardiovascular Disease Case Reports in Urology: Erectile Dysfunction and Cardiovascular Disease - Neil Baum, MD Click here to download full article in PDF Case Presentation A 67-year-old man visits his primary care physician with the chief complaint of erectile dysfunction (ED). The low-risk category includes patients in whom sexual activity poses no significant cardiac risk; these patients generally can initiate ED therapy without the need for additional ...
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Hormonal Therapy and Prevention of Cardiovascular Disease in Postmenopausal Women
Heart and Estrogen/progestin Replacement Study In 1998, the first findings from the Heart and Estrogen/progestin Replacement Study4 (HERS) further unseated the beneficial role of estrogen in maintaining cardiovascular health. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Postmenopausal hormone therapy and risk of stroke: The Heart and Estrogen-progestin Replacement Study (HERS).
Featured Content from Clinical Geriatrics
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Treatment of Older Persons with Hypertension
Treatment of Older Persons with Hypertension Cardiovascular Disease: Treatment of Older Persons with Hypertension- Wilbert S. Aronow, MD Click here to download full article in PDF Older persons are more likely to have hypertension and isolated systolic hypertension. 28. Aronow WS, Ahn C. Incidence of new coronary events in older persons with prior myocardial infarction and systemic hypertension treated with beta blockers, angiotensin-converting enzyme inhibitors, diuretics, calcium ...
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Abstracts from Medical Literature for the Geriatrics Practitioner
Arch Intern Med 2004;164:55-60. ADDITIVE BENEFITS OF PRAVASTATIN AND ASPIRIN TO DECREASE RISKS OF CARDIOVASCULAR DISEASE Randomized trials of secondary prevention have shown pravastatin sodium and aspirin to reduce the risk of cardiovascular disease. It is suggested that health care providers should use the Vaccine Information Sheets developed by the Centers for Disease Control and Prevention to inform patients about the risks and benefits associated with the influenza and pneumococcal ...
Featured Content from Annals of Long-Term Care
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CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes
CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes CME Article: Cardiovascular Disease Risk and Evidence-Based Risk Reduction in Type 2 Diabetes By James B. Meigs, M.D., M.P.H. 7 During nine years of follow-up of over 5,000 newly diagnosed patients with type 2 diabetes in the United Kingdom Prospective Diabetes Study (UKPDS), CVD complications outnumbered microvascular complications an overwhelming 70 to 1.8 Given the increasing prevalence of ...
Featured Content from Clinical Geriatrics
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